#2 cly is missing, would like to know if plug or wire

jrcorbett, it would help if you would tell us what engine you have? What transmission, how many miles, last tune-up etc. Also you should tell us if the Service engine light is on or not. The first thing I would do is to hook it up to a scanner and see if the computer throws any codes. There is a whole lot more than the plugs or wires that could cause this. Of course, you may also just want to tune it up, change the plugs and take a look at the plug face and see what it tells you regarding your combustion etc. Hope this help, good luck.