replaced lcd replace will not slide to unlock

Double check your connections, the digitizer(glass) can be a bit of a pain to get to stay.

I am having the exact same problem! I have an ipod touch 2nd gen that I recently bought off ebay and the only problem the guy said it had was the screen would not open. I opened the ipod touch, cleaned it and looked around at the parts and everything looks ok, though I noticed from the headphone jack that the ipod has gotten wet. Everything else from what I know so far works great. The ipod powers up, is recognized by itunes, the battery charges, lcd screen works, I have restored it several times, updated the firmware, and it syncs. I have tried two different screens: #821-0627-03 and 04 but neither is working. I am about to pull my hair out trying to figure out why this screen would not be working! I keep looking at the connector thinking it may have some corrosion inbetween the pins but I can't tell (even with a magnifier) if that's just the color that's off or actual corrosion. I have cleaned the connector also with 90%+ Alcohol, too. Help Help Help PLEASE!