2013 ram 1500 5.7 all injector circuits open runs with misfire cyl 1

First things first: GET IT SCANNED. We need specific codes. These codes are bad news; the last thing you want to see is P2302 and P3497. They often point to 5.7 oil consumption.

That said, I have seen these 5.7 engines have issues with major oil consumption when they are still young (think 125k or fewer miles), where the misfire is caused by oil in the combustion chamber. Check the oil levels. If the level is low, the engine has a very high chance of the problem being related to a bad short block where oil is getting in the combustion chamber :-(.

First thing I would do before condemning the engine is take the ignition coils and plugs out (check all 8), and check for evidence of fouling of the plugs with oil, or even a damaged plug that broke due to an unresolved misfire that was left too long. A lot of the time, this occurs on the 5.7 Hemi, where this occurs on the driver side so check that first. Sometimes the other side (passenger) is fine, but very often the damage is so bad on these engines that the damage will foul plugs frequently enough you can't swap the plugs at an accelerated rate to compensate like we do with the old 2AZ-FE Toyotas which were known to burn oil similarly (2002-2006, 2007-2009 2AZ VX40 with the 2AZ is suspect too). The moment you see multiple plugs come out with oil is a bad sign, the engine is on borrowed time :-(. If you keep it going, pray it doesn't blow up and lock up; rather limps home so you can AT LEAST get it in a parking lot if all else fails.