However, the four "1.5 mm Phillips screws", in each of the four corners, will need to be completely removed (and, subsequently, replaced during re-assembly).
If your objective is to remove the front panel only, you do not need to remove any of the "large-headed" 1.5 mm Phillips screws, but only loosen them slightly. Putting these screws back can be quite a hassle, and there's really no need for it. When replacing the front panel, take care of the position of the washers (they should be in between the case and screw head.
Just be careful when removing the battery with the plastic pull tab. On some units, they use so much glue that it's virtually impossible to take the battery.
In such an instance, you could use the iPod opening tool to assist (just be careful where you stick it!)